Monthly Archives: June 2017
ASCO: CAR T-Cell Therapy Promising in Multiple Myeloma
June 6, 2017 (HealthDay News)
Findings from trial of chimeric antigen receptor T cells targeting B-cell maturation protein
A new type of immunotherapy appears to...
VIDEO: Long and deep responses to CAR T-cell therapies in multiple myeloma
June 25, 2017 (VJHemOnc)
CAR T-cells seem to be taking the hematology world by storm. Here. Rakesh Popat, MD, PhD from the University College London,...
“Immunoswitch” particles may be key to more-effective cancer immunotherapy
June 12, 2017 (Medical News Today)
A nanoparticle has been created by scientists at Johns Hopkins, supporting two unique antibodies that may have the...
StatPearls Question of the Week – #7
So far in the early clinical trials, chimeric antigen receptor-engineered T cells (CAR-T cells) have targeted which receptor in the treatment of acute lymphoblastic...
VIDEO: CAR-T Therapy – How does it work?
February 28, 2017 (Kite Pharma)
See how CAR-T Therapy Works in this video from Kite Pharma.
CAR T-Cell Therapy HCP Guide – Side Effects: Tumor Lysis Syndrome
Tumor lysis syndrome (TLS) is another known and expected side effect of CAR T-cell therapy. TLS occurs due to cell death and sunsequent release...
CAR T-Cell Therapy HCP Guide – Side Effects: B Cell Aplasia
One of the advantages of CAR T-cell therapy that targets the C19 tumor antigen is that C19 is not found on other cells except...
CAR T-Cell Therapy HCP Guide – Side Effects: Cerebral Edema
Cerebral edema (brain swelling) is another very serious and often fatal adverse event encountered with CAR T treatment.
Eight cerebral edema-related deaths have been reported...
CAR T-Cell Therapy HCP Guide – Side Effects: Neurotoxicity
Neurotoxicity, which can occur in tandem with cytokine release syndome (CRS), includes symptoms such as aphasia, tremor, and seizures. Other reported CNS events include...
CAR T-Cell Therapy HCP Guide – Side Effects: Cytokine Release Syndrome (CRS)
Cytokine Release Syndrome (CRS) is one of the most common, but worrisome, serious side effects of CAR T-cell therapy. How does it occur? After...
