June 6, 2017 (HealthDay News) Findings from trial of chimeric antigen receptor T cells targeting B-cell maturation protein A new type of immunotherapy appears to provide long-lasting protection against multiple …
ASCO: CAR T-Cell Therapy Promising in Multiple Myeloma Read More
June 25, 2017 (VJHemOnc) CAR T-cells seem to be taking the hematology world by storm. Here. Rakesh Popat, MD, PhD from the University College London, London, UK talks to us …
VIDEO: Long and deep responses to CAR T-cell therapies in multiple myeloma Read More
June 12, 2017 (Medical News Today) A nanoparticle has been created by scientists at Johns Hopkins, supporting two unique antibodies that may have the power of “switching off” destructive properties …
“Immunoswitch” particles may be key to more-effective cancer immunotherapy Read More
So far in the early clinical trials, chimeric antigen receptor-engineered T cells (CAR-T cells) have targeted which receptor in the treatment of acute lymphoblastic leukemia? A. CD5 B. CD19 C. …
StatPearls Question of the Week – #7 Read More
February 28, 2017 (Kite Pharma) See how CAR-T Therapy Works in this video from Kite Pharma.
VIDEO: CAR-T Therapy – How does it work? Read More
Tumor lysis syndrome (TLS) is another known and expected side effect of CAR T-cell therapy. TLS occurs due to cell death and sunsequent release of content into the bloodstream. Multiple …
CAR T-Cell Therapy HCP Guide – Side Effects: Tumor Lysis Syndrome Read More
One of the advantages of CAR T-cell therapy that targets the C19 tumor antigen is that C19 is not found on other cells except B cells, sparing other healthy tissues. …
CAR T-Cell Therapy HCP Guide – Side Effects: B Cell Aplasia Read More
Cerebral edema (brain swelling) is another very serious and often fatal adverse event encountered with CAR T treatment. Eight cerebral edema-related deaths have been reported to date. Reports of 5 …
CAR T-Cell Therapy HCP Guide – Side Effects: Cerebral Edema Read More
Neurotoxicity, which can occur in tandem with cytokine release syndome (CRS), includes symptoms such as aphasia, tremor, and seizures. Other reported CNS events include ataxia and confusion. The mechanisms leading …
CAR T-Cell Therapy HCP Guide – Side Effects: Neurotoxicity Read More
Cytokine Release Syndrome (CRS) is one of the most common, but worrisome, serious side effects of CAR T-cell therapy. How does it occur? After engineering, the CAR T-cells are reinfused …
CAR T-Cell Therapy HCP Guide – Side Effects: Cytokine Release Syndrome (CRS) Read More