Drugs.com
CAR T-Cell Therapy HCP Guide – Future Implications for CAR T-Cell Therapy
What's Next for CAR T-Cell Therapy?
Top issues for researchers and clinicians utilizing CAR T-cell therapy include:
Shortening the manufacturing time and vein-to-vein time, scaling...
CAR T-Cell Therapy HCP Guide – The Costs Involved in CAR T-Cell Therapy
Costs and Payer Questions
A patient-specific and complicated manufacturing process such as CAR T is expected to be costly. The cost of the first...
CAR T-Cell Therapy HCP Guide – CAR T-Cell Therapy’s Effect on the Healthcare System
CAR T-Cell Therapy: A Viable Option?
Chimeric antigen receptor (CAR) T-cell therapy is the first form of gene therapy approved in the U.S. CAR...
CAR T-Cell Therapy HCP Guide – The Next Generation for T-Cell Receptor Therapy
T-Cell Receptor Therapy: The Next Generation
T cells are one type of lymphocyte important for the immune system to function properly. As with CAR T-cell...
CAR T-Cell Therapy HCP Guide – Challenges: Car-T and Solid Tumors
The Challenging Solid Tumor Microenvironment
The challenging tumor microenvironment is another obstacle with CAR T-cell therapy of solid tumors.
As reported by Newick and colleagues,...
CAR T-Cell Therapy HCP Guide – Solid Tumors
Solid Tumor Research: Ongoing
CAR T-cell therapy has shown great success in hematologic malignancies, such as non-Hodgkin's lymphoma (diffuse large B-cell lymphoma (DLBCL), follicular...
CAR T-Cell Therapy HCP Guide – Efficacy and Safety of Zuma Trials
ZUMA-3 and ZUMA-4 Trials
In addition to the October 2017 approval for Non-Hodgkin lymphoma, Yescarta (axicabtagene ciloleucel) has shown impressive early results in difficult-to-treat patients...
CAR T-Cell Therapy HCP Guide – Use of Yescarta in Acute Lymphoblastic Leukemia
Use of Yescarta in Acute Lymphoblastic Leukemia
Yescarta (axicabtagene ciloleucel) is also under late Phase 1 research for treatment of refractory or relapsed acute...
CAR T-Cell Therapy HCP Guide – Is There A Universal CAR-T Cell Therapy?
Creating a universal CAR T agent could help avoid the lengthy and sometimes dangerous time period from apheresis of T-cells to re-infusion, which on...
CAR T-Cell Therapy HCP Guide – What Studies Are Ongoing With CAR T-Cell Therapy?
While side effects can be challenging, the fact remains that complete and partial remissions are impressive with CAR T-cell therapy. All eligible patients have...
