There is some experimental work using chimeric antigen receptor engineered T cells (CAR-T cells) for therapy to target cancer stem cells. What CD receptor is being considered an attractive therapeutic …
StatPearls Question of the Week – #10 Read More What are present hurdles faced with chimeric antigen receptor-engineered T cells (CAR-T cells) therapy? A. Antigen loss relapse B. On target/off tumor toxicity C. Less efficacy in solid tumors D. …
StatPearls Question of the Week – #9 Read More Which condition has not been shown to respond to chimeric antigen receptor-engineered T cells (CAR-T cells) therapy? A. Non-Hodgkin lymphoma B. Acute lymphoblastic leukemia C. Chronic lymphocytic leukemia D. Meningioma …
StatPearls Question of the Week – #8 Read More So far in the early clinical trials, chimeric antigen receptor-engineered T cells (CAR-T cells) have targeted which receptor in the treatment of acute lymphoblastic leukemia? A. CD5 B. CD19 C. …
StatPearls Question of the Week – #7 Read More To date in clinical trials, chimeric antigen receptor T (CAR-T) cell therapy has been used to treat which type of cancer? A. Sezary syndrome B. Chronic myeloid leukemia C. Mycosis …
StatPearls Question of the Week – #6 Read More In the recent clinical trials involving Chimeric Antigen Receptor T cell therapy (CAR-T), which complication led to a halt in the studies? A. Myocardial infarction B. Disseminated intravascular coagulation C. …
StatPearls Question of the Week – #5 Read More On which malignancies is Chimeric Antigen Receptor T-cell therapy (CAR-T) being tested? A. Solid tumors B. Hematological malignancies C. Sarcomas D. Skin cancers Click for the answer and teaching points.
StatPearls Question of the Week – #4 Read More From the early clinical trials involving chimeric antigen receptor T cell therapy (CAR-T), cytokine release syndrome has been a major problem. To block the high levels of interleukin 6, what …
StatPearls Question of the Week – #3 Read More What is the most common adverse effect of chimeric antigen receptor therapy (CAR-T)? A. Reactivation of tuberculosis B. Stevens-Johnson syndrome C. Cytokine release syndrome D. Neurotoxicity Click for the answer …
StatPearls Question of the Week #2 Read More Based on early clinical trial data, chimeric antigen receptor therapy (CAR-T) has been most successful in which population? A. Children with acute lymphocytic leukemia B. Adults with chronic myeloid leukemia …
StatPearls Question of the Week #1 Read More