March 1, 2017 (The Scientist) In the 6-month follow-up for a Phase 2 trial focused on 101 advanced non-Hodgkin lymphoma patients who underwent chimeric antigen receptor T-cell (CAR-T) therapy, 41 …
Kite’s CAR T-Cell Therapy Success Read More
Many researchers, oncologists, and pharmaceutical companies hail CAR-T therapy as a “cure for cancer.” But what exactly is this evolving technology? How is it expected to revolutionize oncology? Here are …
14 scientific definitions for a deeper understanding of CAR-T therapy Read More
October 17, 2016 (CNBC) Arie Belldegrun, Kite Pharma CEO talks to CNBC’s Meg Tirrell about developing cancer immunotherapy drugs with T-cells. Also Belldegrun address the question about pricing the product …
VIDEO: Interview with Arie Belldegrun, Kite Pharma CEO on pricing Read More
January 5, 2017 (ScienceDaily.com) Lymphoma, the most common blood cancer, is the result of the uncontrollable multiplication of lymphocytes (immune cells). B-cell lymphomas account for 85% of patients who have …
Immune cell therapy shows promising results for lymphoma patients Read More
In the recent clinical trials involving Chimeric Antigen Receptor T cell therapy (CAR-T), which complication led to a halt in the studies? A. Myocardial infarction B. Disseminated intravascular coagulation C. …
StatPearls Question of the Week – #5 Read More
February 6, 2017 (The Journal of Clinical Investigation) Part of the reason why treatment of solid tumors using CAR T-cells has been troublesome is because of adenosine production. Production of …
Targeting Adenosine 2A Receptors Enhances CAR T-Cell Efficacy Read More
January 26, 2017 (HealthDay News) Modified T cells from healthy donor allowed infants to reach remission, researchers report Two infants with B-cell acute lymphoblastic leukemia (ALL) are in remission after …
Universal CAR T-Cell Therapy Helped Treat ALL in Two Infants Read More
May 22, 2017 (Medical News Today) An antibody originally developed to study multiple sclerosis has been found to precisely target T cells that can kill cancer cells. Researchers at Brigham …
Antibody That Precisely Targets T Cells Discovered Read More On which malignancies is Chimeric Antigen Receptor T-cell therapy (CAR-T) being tested? A. Solid tumors B. Hematological malignancies C. Sarcomas D. Skin cancers Click for the answer and teaching points.
StatPearls Question of the Week – #4 Read More
CAR T-Cell Therapy and Checkpoint Inhibitors Together? CAR T-cell therapy positive response rates in aggressive leukemias and lymphomas are impressive, but relapse or progression does occur in some patients after …
CAR-T Cell Therapy HCP Guide – KTE-C19 Studies – Zuma 6 Trials Read More